Vol. 20 Núm. 79 (2020)


J. Güereca-Arvizuo
Universidad Autónoma de Ciudad Juárez
A. Ramos-Jiménez
Universidad Autónoma de Ciudad Juárez
V. Moreno-Brito
Universidad Autónoma de Chihuahua
M. Cervantes-Borunda
Universidad Autónoma de Chihuahua
R.P. Hernández-Torres
Universidad Autónoma de Chihuahua
Publicado septiembre 30, 2020

Palabras clave:

Alfa-actinina-3, creatina quinasa, genética deportiva, polimorfismo genético
Cómo citar
Güereca-Arvizuo, . J., Ramos-Jiménez, . A., Moreno-Brito, V., Cervantes-Borunda, M., & Hernández-Torres, R. (2020). RESPUESTA DE CREATINA QUINASA A UN EJERCICIO ANAEROBIO SUPRAMÁXIMO EN GENOTIPOS DE ACTN3. Revista Internacional De Medicina Y Ciencias De La Actividad Física Y Del Deporte, 20(79), 381-393. https://doi.org/10.15366/rimcafd2020.79.001


El objetivo del presente estudio fue investigar las diferencias en la actividad de la enzima Creatina Quinasa (CK) en pre y post ejercicio anaerobio supramáximo (EASM) en portadores de los genotipos del gen de la alfa-actinina-3 (ACTN3). Se reclutaron 39 hombres sanos físicamente activos (18-35 años) y se sometieron a un EASM de 30 s (Wingate). El gen ACTN3 se determinó a partir del ADN de glóbulos blancos en sangre periférica y se evaluó la actividad de la CK en muestras sanguíneas en condiciones basales, a las 24 y 48 h post EASM. Los portadores del genotipo XX vs RR presentaron 1,4 veces menor actividad de CK en condiciones basales (p<0,05) y una mayor actividad de CK a las 24 h post ejercicio (p<0,05). Una serie de EASM fue capaz de causar un incremento significativo de la actividad de CK a las 24 h en los portadores del genotipo XX.


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