Vol. 18 Núm. 71 (2018)


G.A. Pussieldi
Universidade Federal de Viçosa
C.E. Veneroso
Universidade Federal do Maranhão
J.A. De Paz
Instituto de Ciencias Biomédicas (España)
M.M Teixeira
Instituto de Ciências Biológicas (Brasil)
Publicado septiembre 18, 2018
Cómo citar
Pussieldi, G., Veneroso, C., De Paz, J., & Teixeira, M. (2018). RESPUESTA INFLAMATORIA Y ANTIINFLAMATORIA TRAS EL ESFUERZO AGUDO EN NATACIÓN // INFLAMMATORY AND ANTINFLAMMATOY RESPONSE AFTER SWIMMING ACUTE EFFORT. Revista Internacional De Medicina Y Ciencias De La Actividad Física Y Del Deporte, 18(71). https://doi.org/10.15366/rimcafd2018.71.001



El objetivo del estudio fue analizar la respuesta inflamatoria y antiinflamatoria a un esfuerzo agudo e intenso de natación, durante la fase preparatoria para los campeonatos nacionales absolutos brasileños. Participaron 20 nadadores. Se determinaron las concentraciones plasmáticas de IL-6, TNF-?, sTNFR1, IP-10 y MCP-1, antes y 40 minutos después de 2 series de 4 repeticiones de 50 metros nadados a la máxima intensidad con 3 minutos de recuperación entre cada repetición y una recuperación activa nadando 1500m a intensidad suave después de cada una de las dos series.  En respuesta al ejercicio agudo únicamente la concentración sTNFR1 se redujo, no presentando cambios en IP 10, IL-6 ni TNF-?. Por tanto el ejercicio agudo en natación en personas bien entrenadas no parece producir una respuesta inflamatoria.

PALABRAS CLAVE: natación, citoquinas, quimiocinas.



The mean of the study was to analyze the inflammatory and anti-inflammatory response to an intense and intense swimming effort during the preparatory phase for the Brazilian National Adult Championship. Twenty swimmers participated. Plasma concentrations of IL-6, TNF-?, sTNFR1, IP-10 and MCP-1 were determined before and 40 minutes after 2 sets of 4 repetitions of 50 meters swam at maximum intensity with 3 minutes of recovery between each repetition and an active recovery swimming 1500m at low intensity after each of the two series. In response to acute exercise only the sTNFR1 concentration was reduced, with no changes in IP-10, IL-6 or TNF-?. Thus, acute exercise in swimming in well-trained people does not seem to produce an inflammatory response.

KEY WORDS: swimming, citokynes, chemokines.


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Ahima RS, Park HK. Connecting Myokines and Metabolism. Endocrinol Metab (Seoul). 2015 Sep;30(3):235-45. https://doi.org/: 10.3803/EnM.2015.30.3.235. Epub 2015 Aug 4.

Allen J, Sun Y, Woods JA. Exercise and the regulation of inflammatory responses. Prog Mol Biol Transl Sci. 2015;135:337-54. https://doi.org/: 10.1016/bs.pmbts.2015.07.003. Epub 2015 Jul 31.

Deyhle MR, Gier AM, Evans KC, Eggett DL, Nelson WB, Parcell AC, Hyldahl RD. Skeletal muscle inflammation following repeated bouts of lengthening contractions in humans. Front Physiol.2016 Jan 12;6:424. https://doi.org/: 10.3389/fphys.2015.00424.

Fehrenbach E, Schneider ME. Trauma-induced systemic inflammatory response versus exercise-induced immunomodulatory effects. Sports Med 2006;36(5):373-384.

Fischer CP, Plomgaard P, Hansen AK, Pilegaard H, Saltin B, Pedersen BK. Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle. Am J Physiol Endocrinol Metab 2004; 287: E1189-E1194.

Gleeson M, Walsh NP. The BASES expert statement on exercise, immunity, and infection. J Sports Sci. 2012; 30(3): 321-324. https://doi.org/: 10.1080/02640414.2011.627371

Harnish CR, Sabo RT. Comparison of two different sprint interval training work-to-rest ratios on acute inflammatory responses. Sports Med. 2016; 2:20. https://doi.org/ 10.1186/s40798-016-0044-1

King DE, Carek P, Maionous AG, Pearson WS. Inflammatory markers and exercise: differences related to exercise type. Med Sci Sports Exerc 2003;35(4):575-581.

Li T-L, Gleeson M. The effects of carbohydrate supplementation during the second of two prolonged cycling bouts on immunoendocrine responses. Eur J Appl Physiol 2005;95(5-6):391-399.

Morgado JM, Rama L, Silva I, Inácio MJ, Henriques A, Laranjeira P, Pedreiro S,·Rosado F, Alves F, Gleeson M, Pais ML, Paiva A, Teixeira AM. Cytokine production by monocytes, neutrophils, and dendritic cells is hampered by long-term intensive training in elite swimmers. Eur J Appl Physiol 2012; 112(2):471-482. https://doi.org/ 10.1007/s00421-011-1966-4 123

Morici G, Zangla D, Santoro A, Pelosi E, Petrucci E, Goia M, Bonanno A, Profita M, Bellia V, Testa U, Bonsignore MR. Supramaximal exercise mobilizes hematopoietic progenitors and reticulocytes in athletes. Am J Physiol Regulatory Integrative Comp Physiol 2005;289(5):R1496-R1503.

Nemet D, Rose-Gottron CM, Mills P.J, Cooper DM. Effect of water polo practice on cytokines, growth mediators, and leukocytes in girls. Med Sci Sports Exerc 2003;35(2):356-363.

Nieman DC, Henson DA, Smith LL, Utter AC, Vinci DM, Davis JM,Kaminsky DE, Shute M. Cytokine changes after a marathon race. J Appl Physiol 2001;91(1):109-114.

Pedersen BK, Steensberg A, Keller P, Keller C, Fischer C, Hiscock N, Van Hall G, Plomgaard P, Febbraio MA. Muscle-derived interleukin-6:lipolytic,anti-inflammatory and immune regulatory effects. Pflugers Arch 2003;446:9-16.

Pussieldi GA, Gomes EC, Veneroso CE, De Paz Fernández JA, Rossi AG, Teixeira MM, Teixeira AL.; Alessandri AL. Soluble tumour necrosis factor receptor-1 (sTNFR1) levels are positively associated with exercise intensity in athletes after strenuous off-road cycling. J Sports Med Phys Fitness (Testo stampato). 2014; 54:225-231.

Pyne DB, Gleeson M. Effects of intensive exercise training on immunity in athletes. Int J Sports Med 1998;19(Suppl 3):S183-S191;discussion S191-S194.

Robson PJ. Elucidating the unexplained underperformance syndrome in endurance athletes: the interleukin-6 hypothesis. Sports Med 2003;33(10):771-781.

Smith LL. Cytokine hypothesis of overtraining: a physiological adaptation to excessive stress? Med Sci Sports Exerc 2000;32(2):317-331.

Suzuki K, Peake J, Nosaka K, Okutsu M, Abbis CR, Surriano R, Bishop D, Quod MJ, Lee H, Martin DT, Laursen PB. Changes in markers of muscle damage, inflammation and HSP70 after an Ironman triathlon race. Eur J Appl Physiol 2006;98(6):525-534.

Walsh NP, Gleeson M, Shephard RJ, Gleeson M, Woods JA, Bishop NC, Fleshner M, Green C, Pedersen BK, Hoffman-Goetz L, Rogers CJ, Northoff H, Abbasi A, Simon P. Position statement. Part one: Immune function and exercise. Exerc Immunol Rev. 2011a, 17:6-63.

Walsh NP, Gleeson M, Pyne DB, Nieman DC, Dhabhar FS, Shephard RJ, Oliver SJ, Bermon S, Kajeniene A. (b) Position statement. Part two: Maintaining immune health. Exerc Immunol Rev. 2011b;17:64-103.

Willoughby DS, Vanenk C, Taylor L. Effects of concentric and eccentric contractions on exercise-induced muscle injury, inflammation, and serum IL-6. JEPonline 2003;6(4):8-15.